BDBM195938 US9206199, 43
SMILES Cc1cc(ncc1CC(=O)N1CCN2C[C@@H](OC[C@@H]2C1)c1ccc(F)c([N+]#[C-])c1C)-n1cnnn1
InChI Key InChIKey=AVPSFGWNHXBFAB-GHTZIAJQSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 195938
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 90nMAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair