BDBM19704 (2S)-3-cyclohexyl-2-(furan-3-ylformamido)-N-(2-{[4-(trifluoromethoxy)phenyl]amino}ethyl)propanamide::arylaminoethyl amide deriv. 18

SMILES FC(F)(F)Oc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccoc2)cc1

InChI Key InChIKey=WYNXACPMFXNYKR-FQEVSTJZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19704   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19704((2S)-3-cyclohexyl-2-(furan-3-ylformamido)-N-(2-{[4...)
Affinity DataKi:  6nM ΔG°:  -11.7kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19704((2S)-3-cyclohexyl-2-(furan-3-ylformamido)-N-(2-{[4...)
Affinity DataKi:  914nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19704((2S)-3-cyclohexyl-2-(furan-3-ylformamido)-N-(2-{[4...)
Affinity DataKi:  9.34E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed