BDBM197721 US9216985, 7A
SMILES CC[C@H](Nc1ncnc2[nH]ccc12)c1nc2cccc(F)c2c(=O)n1-c1cccc(CC(F)(F)F)c1
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 197721
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 2.80E+4nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 50nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 5.80E+3nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair