BDBM199117 US9221839, 6f
SMILES CN1C(=N)NC2(COCC2S1(=O)=O)c1ccccc1F
InChI Key InChIKey=JEUWZBSZTAEEME-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 199117
Affinity DataKi: 4.20E+3nM ΔG°: -7.45kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair
Affinity DataKi: 7.85E+3nM ΔG°: -7.08kcal/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50
values for inhibitors of the soluble human BACE1 catalytic domain. This
assay ...More data for this Ligand-Target Pair