BDBM19951 3-arylquinazolinone, 1aar::7-hydroxy-5-(hydroxymethyl)-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one

SMILES OCc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12

InChI Key InChIKey=ZPKUQXYUNFFPKO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19951   

TargetEstrogen receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19951(3-arylquinazolinone, 1aar | 7-hydroxy-5-(hydroxyme...)
Affinity DataIC50:  24nM EC50:  4.46E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19951(3-arylquinazolinone, 1aar | 7-hydroxy-5-(hydroxyme...)
Affinity DataIC50:  121nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed