BDBM19956 3-arylquinazolinethione, 1bd::7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydroquinazoline-4-thione

SMILES Cc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=S)c12

InChI Key InChIKey=GHMWCNIIKUZAOU-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19956   

TargetEstrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19956(3-arylquinazolinethione, 1bd | 7-hydroxy-3-(4-hydr...)
Affinity DataIC50:  1.75E+3nM EC50:  1.67E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19956(3-arylquinazolinethione, 1bd | 7-hydroxy-3-(4-hydr...)
Affinity DataIC50:  79nMAssay Description:Inhibition of estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19956(3-arylquinazolinethione, 1bd | 7-hydroxy-3-(4-hydr...)
Affinity DataIC50:  79nM EC50:  222nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed