BDBM19958 3-arylquinazolinethione, 1bf::5,7-dihydroxy-3-(5-hydroxypyridin-2-yl)-3,4-dihydroquinazoline-4-thione

SMILES Oc1ccc(nc1)-n1cnc2cc(O)cc(O)c2c1=S

InChI Key InChIKey=ARDGKRAEEBANRD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19958   

TargetEstrogen receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19958(3-arylquinazolinethione, 1bf | 5,7-dihydroxy-3-(5-...)
Affinity DataIC50:  515nM EC50:  173nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19958(3-arylquinazolinethione, 1bf | 5,7-dihydroxy-3-(5-...)
Affinity DataIC50:  2.76E+4nM EC50:  4.86E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed