BDBM20119 (2S)-N-(cyanomethyl)-3-phenyl-2-(phenylformamido)propanamide::phenylalanine derivative, 43
SMILES O=C(NCC#N)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
InChI Key InChIKey=WEIUVZVWLANUJJ-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 20119
Affinity DataKi: 62nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
Affinity DataKi: 77nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataKi: >330nMpH: 6.0Assay Description:Inhibition of human liver cathepsin B using Cbz-Arg-Arg-pNA as substrate at pH 6 incubated for 30 mins measured for 20 mins by photometrical analysisMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
University Of S£O Paulo Avenue Trabalhador Sancarlense
Curated by ChEMBL
University Of S£O Paulo Avenue Trabalhador Sancarlense
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Covalent inhibition of Trypanosoma cruzi cruzipain using Z-Phe-Arg-7-amidomethylcoumarin as substrate measured after 5 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
University Of S£O Paulo Avenue Trabalhador Sancarlense
Curated by ChEMBL
University Of S£O Paulo Avenue Trabalhador Sancarlense
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
University Of S£O Paulo Avenue Trabalhador Sancarlense
Curated by ChEMBL
University Of S£O Paulo Avenue Trabalhador Sancarlense
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of papaya papain using Z-Phe-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair