BDBM201751 US9233979, 182::US9233979, 183

SMILES COC[C@@H](NC(=O)Nc1cc2[nH]nc(NCC3CC(C3)C(C)(C)O)c2cn1)c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 201751   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201751(US9233979, 182 | US9233979, 183)
Affinity DataIC50:  3.60nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201751(US9233979, 182 | US9233979, 183)
Affinity DataIC50:  2.60nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent