BDBM202028 (e)-(1-(6-(2-(6-chloro-4-(dimethylamino)quinazolin-2-yl)vinyl)pyridin-2-yl)pyrrolidin-3-yl)methanol::US9540384, 25
SMILES CN(C)c1nc(\C=C\c2cccc(n2)N2CCC(CO)C2)nc2ccc(Cl)cc12
InChI Key InChIKey=MAMFOHPRHXLJLC-VQHVLOKHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 202028
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 220nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair