BDBM204665 1-(5-butoxy-2-fluoro-phenyl)-4-methyl-8-trifluoromethyl-[1,2,4]triazoo[4,3-a]quinoxaline::US9540379, 67

SMILES CCCCOc1ccc(F)c(c1)-c1nnc2c(C)nc3ccc(cc3n12)C(F)(F)F

InChI Key InChIKey=ZVLRIXKYIRCWLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204665   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM204665(1-(5-butoxy-2-fluoro-phenyl)-4-methyl-8-trifluorom...)
Affinity DataIC50:  3nMAssay Description:The DNA encoding PDE2A (NM002599) was cloned and the gene was inserted in the baculovirus and the enzyme-protein expressed in SF21-cells. The enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM204665(1-(5-butoxy-2-fluoro-phenyl)-4-methyl-8-trifluorom...)
Affinity DataIC50: >1.00E+3nMAssay Description:The DNA of PDE10A1 (AB 020593, 2340 bp) was synthesized and cloned into the vector pCR4. TOPO (Entelechon GmbH, Regensburg, Germany). The gene was th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent