BDBM20539 4-Oxopyrimidine, 28a::8-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinoline

SMILES FC(F)(F)c1ccc(cc1)-c1cc(Oc2cccc3cccnc23)ncn1

InChI Key InChIKey=MWBFGQRKOLHTKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20539   

LigandPNGBDBM20539(4-Oxopyrimidine, 28a | 8-({6-[4-(trifluoromethyl)p...)
Affinity DataIC50: >4.00E+3nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20539(4-Oxopyrimidine, 28a | 8-({6-[4-(trifluoromethyl)p...)
Affinity DataIC50:  15nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed