BDBM20539 4-Oxopyrimidine, 28a::8-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinoline
SMILES FC(F)(F)c1ccc(cc1)-c1cc(Oc2cccc3cccnc23)ncn1
InChI Key InChIKey=MWBFGQRKOLHTKZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 20539
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Amgen
Amgen
Affinity DataIC50: >4.00E+3nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Amgen
Amgen
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair