BDBM210932 UCP1191

SMILES CCc1nc(N)nc(N)c1C#CC(C)c1cc2OCOc2c(c1)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=NQHZOWBSMCFILX-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 210932   

TargetDihydrofolate reductase(Staphylococcus aureus)
University of Connecticut

LigandPNGBDBM210932(UCP1191)
Affinity DataIC50:  10nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDihydrofolate reductase(Staphylococcus aureus)
University of Connecticut

LigandPNGBDBM210932(UCP1191)
Affinity DataIC50:  41nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase type 1 from Tn4003(Staphylococcus aureus)
University of Connecticut

LigandPNGBDBM210932(UCP1191)
Affinity DataIC50:  320nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
University of Connecticut

LigandPNGBDBM210932(UCP1191)
Affinity DataIC50:  87nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed