BDBM212006 US9290485, 38

SMILES Cc1cc(N)nc(C)c1CNC(=O)c1cn(Cc2ccc(Oc3ccccc3)cc2)nn1

InChI Key InChIKey=MHSBTTJCQQJZNU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212006   

TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212006(US9290485, 38)
Affinity DataIC50:  19nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in â¿¿assay bufferâ¿¿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent