BDBM213164 US9278963, 011
SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Nc2ccc(Cl)c(Cl)c2)c2ccccc2)nc1
InChI Key InChIKey=GYQVXGALDLQOSD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 213164
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+3nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 177nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair