BDBM218251 US9284333, 16a::US9884860, Example 16a

SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccccc1

InChI Key InChIKey=LLAVWQQOTBFOFF-QFBILLFUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218251   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM218251(US9284333, 16a | US9884860, Example 16a)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The effect of compounds of the formula I on the cloned human cardiac hERG channel was evaluated in an in vitro model using a whole-cell patch-clampin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM218251(US9284333, 16a | US9884860, Example 16a)
Affinity DataIC50:  69nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM218251(US9284333, 16a | US9884860, Example 16a)
Affinity DataIC50:  69nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In DepthDetails US Patent