BDBM220795 US9296759, 31

SMILES CCOc1cccnc1Nc1ccc2Oc3c(F)cc(OC)cc3C3(CCOC(N)=N3)c2c1

InChI Key InChIKey=SDQYMEUFNUKCHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220795   

TargetCathepsin D(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM220795(US9296759, 31)
Affinity DataIC50:  4.00E+5nMpH: 3.5Assay Description:Recombinant CathepsinD was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cathepsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM220795(US9296759, 31)
Affinity DataIC50:  69.6nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent