BDBM22116 aza-peptide Michael acceptor, 7b::benzyl (2E)-3-{N'-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}propanamido]propanoyl]-N-(carbamoylmethyl)hydrazinecarbonyl}prop-2-enoate

SMILES C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)NN(CC(N)=O)C(=O)C=CC(=O)OCc1ccccc1

InChI Key InChIKey=LAOGMMDQFBFYCI-OALUTQOASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22116   

TargetLegumain(Schistosoma mansoni)
Georgia Institute of Technology

LigandPNGBDBM22116(aza-peptide Michael acceptor, 7b | benzyl (2E)-3-{...)
Affinity DataIC50:  38nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Ixodes ricinus)
Georgia Institute of Technology

LigandPNGBDBM22116(aza-peptide Michael acceptor, 7b | benzyl (2E)-3-{...)
Affinity DataIC50: <1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClan CD, family C13, asparaginyl endopeptidase-like cysteine peptidase(Trichomonas vaginalis G3)
Georgia Institute of Technology

LigandPNGBDBM22116(aza-peptide Michael acceptor, 7b | benzyl (2E)-3-{...)
Affinity DataIC50:  5nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed