BDBM22145 Biotinylated Michael acceptor, 12::ethyl (2E)-4-[(2S)-2-[(2S)-2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}propanamido]-N'-(carbamoylmethyl)propanehydrazido]-4-oxobut-2-enoate

SMILES [H][C@]12CS[C@@H](CCCCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NN(CC(N)=O)C(=O)C=CC(=O)OCC)[C@@]1([H])NC(=O)N2

InChI Key InChIKey=RBCZSRXBNSOGEJ-GVZUZGFXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22145   

TargetLegumain(Schistosoma mansoni)
Georgia Institute of Technology

LigandPNGBDBM22145(Biotinylated Michael acceptor, 12 | ethyl (2E)-4-[...)
Affinity DataIC50:  10nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Ixodes ricinus)
Georgia Institute of Technology

LigandPNGBDBM22145(Biotinylated Michael acceptor, 12 | ethyl (2E)-4-[...)
Affinity DataIC50:  2.80nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetClan CD, family C13, asparaginyl endopeptidase-like cysteine peptidase(Trichomonas vaginalis G3)
Georgia Institute of Technology

LigandPNGBDBM22145(Biotinylated Michael acceptor, 12 | ethyl (2E)-4-[...)
Affinity DataIC50: <10nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed