BDBM221979 US9303035, 4.2

SMILES Cn1c2c3[C@H](O[C@H](CO)Cn3c(-c3cccc(c3)C#N)c2c(=O)n(C)c1=O)c1nc(Cl)cs1

InChI Key InChIKey=GMANXRNKIWGMRW-DJJJIMSYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221979   

TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis

US Patent
LigandPNGBDBM221979(US9303035, 4.2)
Affinity DataIC50: >30nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent