BDBM221986 US9303035, 8.0a
SMILES Cn1c2c3[C@H](O[C@@H](CO)Cn3c(-c3cccc(Cl)c3)c2c(=O)n(C)c1=O)c1nc(Cl)cs1
InChI Key InChIKey=SBBKQQVCPBSLHK-XIKOKIGWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 221986
TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.0700nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair