BDBM222452 4-(4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamido)-2-fluorophenoxy)-N-(2-morpholinoethyl)picolinamide (9l)

SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(c3)C(=O)NCCN3CCOCC3)c(F)c2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=WZSFRCWKHKFQMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222452   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM222452(4-(4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-p...)
Affinity DataIC50:  860nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM222452(4-(4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-p...)
Affinity DataIC50:  510nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed