BDBM22417 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine::CHEMBL295467::LY 135252::LY 94939::LY135252::LY139602::Nisoxetine::Nisoxetine Inhibitor::US9944618, Compound ID No. 177::[3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine::[3H]Nisoxetine
SMILES CNCCC(Oc1ccccc1OC)c1ccccc1
InChI Key InChIKey=ITJNARMNRKSWTA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 22417
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University
Curated by PDSP Ki Database
Harvard University
Curated by PDSP Ki Database
Affinity DataIC50: >500nMAssay Description:Binding affinity against serotonin transporter (SERT) by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
Affinity DataIC50: >500nMAssay Description:Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as inhibition of dopamine reuptake after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human NET expressed in HEK293 cells assessed as inhibition of noradrenaline reuptake after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as inhibition of serotonin reuptake after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Lundbeck Ais
Curated by PDSP Ki Database
Lundbeck Ais
Curated by PDSP Ki Database
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells after 15 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of DA reuptake at human DAT expressed in HEK293 cells after 15 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in HEK293 cells after 15 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair