BDBM227167 US9328106, 114::US9328106, 122::US9328106, 132::US9328106, 133
SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1C1CC(F)(F)CC(N)CO1
InChI Key InChIKey=QYFKQWAZVKFMEO-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 227167
Affinity DataKi: 0.0140nM ΔG°: -14.8kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Affinity DataKi: 0.0140nM ΔG°: -14.8kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Affinity DataKi: 0.0320nM ΔG°: -14.3kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Affinity DataKi: 0.0760nM ΔG°: -13.8kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair