BDBM227311 US9328106, 262

SMILES CO[C@H]1CO[C@@H](CC[C@H]1N)c1c(NC(=O)c2nc(sc2N)-c2c(F)ccc(F)c2F)cnn1C

InChI Key InChIKey=BESIACQRKWNYKW-XBFCOCLRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227311   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM227311(US9328106, 262)
Affinity DataKi:  0.0100nM ΔG°:  -15.0kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent