BDBM227396 US9328106, 348

SMILES CO[C@@H]1CO[C@@H](CC[C@H]1N)c1c(NC(=O)c2csc(n2)-c2ncccc2C)cnn1C

InChI Key InChIKey=NCLVNWAXZPPDBJ-XOKHGSTOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227396   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM227396(US9328106, 348)
Affinity DataKi:  0.0140nM ΔG°:  -14.8kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent