BDBM228232 1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(1-phenyl-1H-pyrazol-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one::US10047084, 21

SMILES Cn1c2cnc3ccc(cc3c2n([C@@H]2CC[C@H](O)CC2)c1=O)-c1cnn(c1)-c1ccccc1

InChI Key InChIKey=IWWZJMKINULDRT-OYRHEFFESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228232   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Beijing Forelandpharma

US Patent
LigandPNGBDBM228232(1-((1s,4s)-4-hydroxycyclohexyl)-3-methyl-8-(1-phen...)
Affinity DataIC50:  55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent