BDBM22977 2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitrophenyl)methoxy]benzamide::CHEMBL147016::Meclofenamic acid derivative, 29

SMILES Cc1ccc(Cl)c(Nc2ccccc2C(=O)NOCc2ccc(cc2)[N+]([O-])=O)c1Cl

InChI Key InChIKey=RKWMWTYLVQBARR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22977   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22977(2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitro...)
Affinity DataIC50:  6.00E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM22977(2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitro...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22977(2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM22977(2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitro...)
Affinity DataIC50:  200nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed