BDBM231619 GSK5750

SMILES On1c2ncccc2c(NCc2cc3ccccc3s2)nc1=O

InChI Key InChIKey=JMKYKCCBXRBHQY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231619   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Mcgill University

LigandPNGBDBM231619(GSK5750)
Affinity DataKd:  387nMpH: 7.8Assay Description:In this case, 1 μM HIV-1 RT was added to 50 mM Tris-HCl (pH 7.8), 50 mM NaCl, 6 mM MgCl2, and varying concentrations of GSK5750 to form enzyme-i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Mcgill University

LigandPNGBDBM231619(GSK5750)
Affinity DataIC50:  330nMpH: 7.8 T: 2°CAssay Description:To compare activity and inhibition of E. coli RNase H with HIV-1 RNase H, theconcentration of the E. coli was adjusted to the efficiency of 500 nM HI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed