BDBM233666 US9353066, 1.119

SMILES Cc1cc(Nc2nccc(C)n2)cc(c1)-c1ccc(cc1)C(C)(O)[C@H]1CC[C@@H](CC1)C(O)=O

InChI Key InChIKey=FZTWDMBZHGQKFT-WKHLBODFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233666   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233666(US9353066, 1.119)
Affinity DataIC50:  6.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent