BDBM234844 US9353116, 13
SMILES CC(C)n1nc(Cc2cccc(c2)C(=O)CF)c2c(N)ncnc12
InChI Key InChIKey=WEPKWIAJJGCTLW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 234844
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Gallus gallus (Chicken))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: >5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533,V323S,T338C](Gallus gallus (Chicken))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 29nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533,V323A,T338C](Gallus gallus (Chicken))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 67nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338C](Gallus gallus (Chicken))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 338nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair