BDBM234969 US9556148, 40::n-(cyanomethyl)-4-(5-methyl-2-((4-(4-morpholinopiperidin-1-yl)phenyl)amino)pyrimidin-4-yl)benzamide
SMILES Cc1cnc(Nc2ccc(cc2)N2CCC(CC2)N2CCOCC2)nc1-c1ccc(cc1)C(=O)NCC#N
InChI Key InChIKey=LKTNBLBEAJCSNG-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 234969
Affinity DataIC50: 1.30nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair