BDBM235383 US10085990, Example 116::US9393245, 116

SMILES COc1cccc2c1ncc1c2n([C@H]2CCN(C2)C(=O)OC(C)(C)C)c(=O)n(-c2cccc(Cl)c2)c1=O

InChI Key InChIKey=CTKRVYLHFHYHOK-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235383   

TargetLipopolysaccharide-induced tumor necrosis factor-alpha factor(Homo sapiens (Human))
Vtv Therapeutics

US Patent
LigandPNGBDBM235383(US10085990, Example 116 | US9393245, 116)
Affinity DataIC50:  2nMAssay Description:Samples were tested for TNF as per the manufacturer's instructions (TNF ELISA; R&D Systems, Cat #DY210). The samples were serially diluted with P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Vtv Therapeutics

US Patent
LigandPNGBDBM235383(US10085990, Example 116 | US9393245, 116)
Affinity DataIC50:  2nMT: 2°CAssay Description:Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent