BDBM235916 US9365508, 383a (3,5-Br2, 4-OMe)

SMILES COc1c(Br)cc(cc1Br)C(=O)NC(=S)Nc1ccc(NC(=O)CCCCN(C)C)cc1

InChI Key InChIKey=AHFKWHKYDJRABX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235916   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Court of The University of St Andrews

US Patent
LigandPNGBDBM235916(US9365508, 383a (3,5-Br2, 4-OMe))
Affinity DataIC50:  1.40E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews

US Patent
LigandPNGBDBM235916(US9365508, 383a (3,5-Br2, 4-OMe))
Affinity DataIC50:  4.72E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent