BDBM235917 US9365508, 392a (3,5-Cl2, 4-OBu)

SMILES CCCCOc1c(Cl)cc(cc1Cl)C(=O)NC(=S)Nc1ccc(NC(=O)CCCCN(C)C)cc1

InChI Key InChIKey=WWIXWGGZNUYYHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235917   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Court of The University of St Andrews

US Patent
LigandPNGBDBM235917(US9365508, 392a (3,5-Cl2, 4-OBu))
Affinity DataIC50:  400nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews

US Patent
LigandPNGBDBM235917(US9365508, 392a (3,5-Cl2, 4-OBu))
Affinity DataIC50:  2.25E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent