BDBM23628 Dipyridamole Analogue, 8::benzyl 4-{2,6-bis[bis(2-hydroxyethyl)amino]-8-(piperazin-1-yl)pyrimido[5,4-d][1,3]diazin-4-yl}piperazine-1-carboxylate

SMILES OCCN(CCO)c1nc(N2CCNCC2)c2nc(nc(N3CCN(CC3)C(=O)OCc3ccccc3)c2n1)N(CCO)CCO

InChI Key InChIKey=DGJUIQONQJDIIP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23628   

TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center

LigandPNGBDBM23628(Dipyridamole Analogue, 8 | benzyl 4-{2,6-bis[bis(2...)
Affinity DataKi:  449nM ΔG°:  -8.57kcal/mole IC50:  7.95E+3nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
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