BDBM238172 US9394293, G156a
SMILES OC[C@H](O)Cc1cnc(c(F)c1)-c1ccc(cc1)C(=O)Nc1nc2ccc(Cl)cc2s1
InChI Key InChIKey=AMUZKWZDRNKLNY-MRXNPFEDSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 238172
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma
US Patent
Purdue Pharma
US Patent
Affinity DataIC50: 28.7nMpH: 7.4Assay Description:One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma
US Patent
Purdue Pharma
US Patent
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:CHO cells stably expressing human TRPV1 (hTRPV1) were used. Functional assessment of heat-induced activation of hTRPV1 was carried out in a cell-base...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma
US Patent
Purdue Pharma
US Patent
Affinity DataIC50: 18.8nMpH: 7.4 T: 2°CAssay Description:Culture medium was removed using an 8-channel-pipette (Rainin, USA) from the 96-well plate and the wells were refilled with 100 μL of loading buff...More data for this Ligand-Target Pair