BDBM238174 US9394293, G159a

SMILES Cc1ccc2nc(NC(=O)c3ccc(cc3)-c3ncc(C[C@@H](O)CO)cc3F)sc2c1

InChI Key InChIKey=DFAAYCJQDRQTTD-QGZVFWFLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238174   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM238174(US9394293, G159a)
Affinity DataIC50:  29.6nMpH: 7.4Assay Description:One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM238174(US9394293, G159a)
Affinity DataIC50:  879nMT: 2°CAssay Description:CHO cells stably expressing human TRPV1 (hTRPV1) were used. Functional assessment of heat-induced activation of hTRPV1 was carried out in a cell-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM238174(US9394293, G159a)
Affinity DataIC50:  13.7nMpH: 7.4 T: 2°CAssay Description:Culture medium was removed using an 8-channel-pipette (Rainin, USA) from the 96-well plate and the wells were refilled with 100 μL of loading buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent