BDBM238766 US9394297, 450

SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(C)c2=O

InChI Key InChIKey=HLPARXMUJBJYFM-SNVBAGLBSA-N

Data  12 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238766   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM238766(US9394297, 450)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human PIM2 (1 to 291 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238766(US9394297, 450)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human PIM1 (15 to 313 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM238766(US9394297, 450)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human PIM3 (16 to 317 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed