BDBM239987 US9403801, 69

SMILES CN(C1CC2CN(CC2C1)C(=O)CC#N)c1nc(Nc2cnn(C)c2)ncc1Cl

InChI Key InChIKey=SADNCPKHQUVYEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239987   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Calitor Sciences

US Patent
LigandPNGBDBM239987(US9403801, 69)
Affinity DataIC50:  41nMpH: 7.0 T: 2°CAssay Description:JAK2 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC, 10 mM MgAcetate and [γ-33P-ATP](s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Calitor Sciences

US Patent
LigandPNGBDBM239987(US9403801, 69)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:JAK1 (h) is incubated with 20 mM Tris/HCl pH 7.5, 0.2 mM EDTA, 500 μM GEEPLYWSFPAKKK, 10 mM MgAcetate and [γ-33P-ATP](specific activity app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent