BDBM24300 (3-{[3-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl)methyl}phenyl) sulfamate::Letrozole derivative, 7

SMILES NS(=O)(=O)Oc1cccc(c1)C(c1cccc(OS(N)(=O)=O)c1)n1cncn1

InChI Key InChIKey=ISQXIINUBJLKNH-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24300   

TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM24300((3-{[3-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50:  99nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM24300((3-{[3-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed