BDBM24316 4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile::Letrozole derivative, 39

SMILES Oc1ccc(cc1Br)C(c1ccc(cc1)C#N)n1cncn1

InChI Key InChIKey=FCWRPKMHVLOWPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24316   

TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM24316(4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed