BDBM243257 US10053454, Example 1::US10196387, Example 1

SMILES Cc1noc(C)c1-c1cc(C(N)=O)c2[nH]c3cc(ccc3c2c1)C(=O)N1CCCCC1

InChI Key InChIKey=HJAUZIIDDGLDMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 243257   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243257(US10053454, Example 1 | US10196387, Example 1)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243257(US10053454, Example 1 | US10196387, Example 1)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243257(US10053454, Example 1 | US10196387, Example 1)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent