BDBM243417 N-(4,4- difluorocyclohexyl)- 5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide::US10053456, 51::US10414761, Example 51::US10968213, Example 51::US9718814, 51::US9920047, 51
SMILES FC1(F)CCC(CC1)NC(=O)c1csc(c1)[C@@H]1C[C@H]1NCC1CCOCC1
InChI Key InChIKey=KLTJYHBSHFQGGL-IAGOWNOFSA-N
Data 18 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 243417
Affinity DataIC50: <100nMAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair