BDBM244004 (s)-n-(2-hydroxy-1-phenylethyl)-2'-((tetrahydro-2h-pyran-4-yl)amino)spiro[cyclobutane-1,5'-pyrrolo[3,4-d]pyrimidine]-6'(7'h)-carboxamide::US9546173, cmpd 77

SMILES OC[C@@H](NC(=O)N1Cc2nc(NC3CCOCC3)ncc2C11CCC1)c1ccccc1

InChI Key InChIKey=QXVIZWGDLYJIAR-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244004   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244004((s)-n-(2-hydroxy-1-phenylethyl)-2'-((tetrahydr...)
Affinity DataIC50:  13nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent