BDBM246879 US10053465, 18::US10065963, Compound 18::US10125150, Example 18::US10336759, # 18::US10479803, Example 18::US10519163, Example 18::US10675284, Example 18::US11084822, Example 18::US11130767, # 18::US11136326, Example 18::US11304949, Compound 18::US11324749, Comp. No. 18::US11406640, Comp. No. 18::US11596632, Comp. No. 18::US20240058343, Compound 18::US9732097, Example 18::{1-(cis-4-{[6-(2- hydroxyethyl)-2- (trifluoromethyl) pyrimidin-4- yl]oxy}cyclohexyl)- 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]azetidin-3- yl}acetonitrile
SMILES OCCc1cc(O[C@H]2CC[C@H](CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)nc(n1)C(F)(F)F
InChI Key
Data 27 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 246879
Affinity DataIC50: <10nMAssay Description:JAK1 pathway inhibitors that can be used for the treatment of cytokine-related diseases or disorders are tested for inhibitory activity of JAK target...More data for this Ligand-Target Pair