BDBM247175 US9434733, 7-(4-fluorophenyl)-2-[4-methyl-1-[[6-(trifluoromethyl)-3-pyridyl]methyl]pyrrolidin-3-yl]-3H-imidazo[5,1-f][1,2,4]triazin-4-one::US9533992, 7-(4-fluorophenyl)-2-[4-methyl-1-[[6-(trifluoromethyl)-3-pyridyl]methyl]pyrrolidin-3-yl]-3H-imidazo[5,1-f][1,2,4]triazin-4-one

SMILES CC1CN(Cc2ccc(nc2)C(F)(F)F)CC1c1nn2c(ncc2c(=O)[nH]1)-c1ccc(F)cc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 247175   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM247175(US9434733, 7-(4-fluorophenyl)-2-[4-methyl-1-[[6-(t...)
Affinity DataIC50:  86nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM247175(US9434733, 7-(4-fluorophenyl)-2-[4-methyl-1-[[6-(t...)
Affinity DataIC50:  86nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM247175(US9434733, 7-(4-fluorophenyl)-2-[4-methyl-1-[[6-(t...)
Affinity DataIC50:  86nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent