BDBM247807 US10112931, Example 411::US9434719, 411 as TFA salt::US9688672, Example 411
SMILES CC(Nc1nccc(n1)N1[C@H](COC1=O)[C@@H](C)C(F)F)c1nc(no1)-c1ccc(Cl)cc1
InChI Key InChIKey=NOOITAIFTJACTE-VBCZDQSUSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 247807
Affinity DataIC50: 756nMpH: 7.5 T: 2°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:The biochemical reactions were performed at room temperature in 384-well Greiner flat-bottom plates (Costar, Cat. No. 781201) using a final reaction ...More data for this Ligand-Target Pair