BDBM248063 SMY-540

SMILES CCCCCC(=O)N[C@@H](COCc1cccc(n1)-c1ccccn1)[C@H](O)c1ccccc1

InChI Key InChIKey=OOIDUPZQOKFSOW-AZGAKELHSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 248063   

TargetSphingomyelinase C(Bacillus cereus)
Tokushima Bunri University

LigandPNGBDBM248063(SMY-540)
Affinity DataKi:  1.30E+3nM ΔG°:  -8.35kcal/mole IC50:  800nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingomyelinase C(Bacillus cereus)
Tokushima Bunri University

LigandPNGBDBM248063(SMY-540)
Affinity DataKi:  1.30E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingomyelinase C(Bacillus cereus)
Tokushima Bunri University

LigandPNGBDBM248063(SMY-540)
Affinity DataIC50:  800nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails