BDBM248152 CA standard inhibitor, 11

SMILES Oc1ccc(cc1CN1CCCCC1)C(=O)\C=C\c1ccccn1

InChI Key InChIKey=NHHBESCTWVZSNX-CSKARUKUSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 248152   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM248152(CA standard inhibitor, 11)
Affinity DataKi:  1.88E+3nM ΔG°:  -7.81kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM248152(CA standard inhibitor, 11)
Affinity DataKi:  4.80E+4nM ΔG°:  -5.89kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Saccharomyces cerevisiae (Baker's yeast))
Ataturk University

LigandPNGBDBM248152(CA standard inhibitor, 11)
Affinity DataKi:  7.91E+4nM ΔG°:  -5.59kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed